With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot going on in the genome editing field. Here’s our primer.
OPINION: A massive bias in medical studies toward men of European origin means that genetic variants in understudied populations don’t get the focus they deserve
Polygenic risk scores — a patient’s chance, based on tiny DNA variants, of developing cardiovascular disease, breast cancer and more — are coming to clinics. But there are kinks to iron out and accuracy remains an issue.
They have held our fascination ever since we first identified their remains. Today, thanks to new artifacts and technologies, findings about our closest relatives are coming thick and fast.
After turning up hundreds of genes with hard-to-predict effects, some scientists are now probing the grander developmental processes that shape face geometry
A scientist whose work was key to identifying, studying and finding treatments for this life-threatening virus discusses the scientific journey and challenges that persist
Scientists agree that eons ago, a bacterium took up residence inside another cell and became its powerhouse, the mitochondrion. But there are competing theories about the birth of other organelles such as the nucleus and endoplasmic reticulum.
Their genital anatomy, musculature and aggressiveness have made them a model for studying the phenomenon of female masculinization — and demonstrate that sometimes, it’s not easy to tell the difference between male and female
As cells divide, they must copy all of their chromosomes once and only once, or chaos would ensue. How do they do it? Key controls happen well before replication even starts.
Genetic conditions like Dravet syndrome, which causes severe childhood epilepsy, are hard to tackle with traditional gene therapy. New approaches in the works include using antisense therapy to boost mRNA splicing.
Paleogenomic research has expanded rapidly over the past two decades, igniting heated debate about handling remains. Who gives consent for study participants long gone — and who should speak for them today?
The way we see and describe hues varies widely for many reasons: from our individual eye structure, to how our brain processes images, to what language we speak, or even if we live near a body of water
Differences between the immune systems of males and females — in particular, ones involving cells called microglia — might help explain why the risk for conditions such as autism and Alzheimer’s varies between the sexes
The world’s natural history collections hold billions of biological specimens, many of which still contain DNA. Scientists exploring these genetic repositories are gaining new, historical perspectives on how animals evolve.
Carminic acid is a bright, natural coloring used in some cosmetics and foods. It’s traditionally sourced from ‘farming’ an insect on acres of prickly pears. Today, scientists are moving to engineer it in microbes.
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